Description
Product Characteristics:
Aliases: AI849156 antibody, alg11 antibody, ALG11_HUMAN antibody, Asparagine-linked glycosylation 11 antibody, Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) antibody, Asparagine-linked glycosylation protein 11 homolog antibody, AW492253 antibody, B230397C21 antibody, GT8 antibody, KIAA0266 antibody, OTTMUSP00000022781 antibody, RGD1564725 antibody
Target Information: This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010]